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SCIENTIFIC SCORE
Likely Very Effective
Based on 3 Researches
9.2
USERS' SCORE
Good
Based on 9 Reviews
8.7
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Oregano (leaf and flower) Oil containing 75% carvacrol (37.5 mg)
50 mg
**
Flaxseed Oil
25 mg
**
Top Medical Research Studies
9
Oregano extract combats type 1 diabetes
Ethyl Acetate Extract of Origanum vulgare L. ssp. hirtum Prevents Streptozotocin-Induced Diabetes in C57BL/6 Mice.
Direct investigation of oregano's effects
We explored the potential of Origanum vulgare L. ssp. hirtum, commonly known as Greek oregano, in the realm of autoimmune disorders, particularly type 1 diabetes (T1D). This study specifically looked at how an ethyl acetate extract of oregano (EAO) could influence the development of T1D in mice.
To conduct the research, researchers induced type 1 diabetes in male C57BL/6 mice using multiple low doses of streptozotocin. They then treated these mice with EAO over ten days. Our findings revealed that EAO not only reduced the incidence of diabetes but also helped preserve pancreatic islets—critical for insulin production.
The results were promising as we observed significant immunomodulatory effects from the oregano extract. In vitro tests indicated that EAO suppressed the activation of immune cells, particularly macrophages and T lymphocytes. Furthermore, it appeared to decrease the levels of certain inflammatory T cell populations and their associated transcription factors, which play a role in promoting inflammation.
These discoveries suggest that oregano extract could potentially serve as a therapeutic option for managing type 1 diabetes by targeting the autoimmune responses involved in the disease. Overall, this study highlights an exciting avenue for plant-based treatments in diabetes management.
To conduct the research, researchers induced type 1 diabetes in male C57BL/6 mice using multiple low doses of streptozotocin. They then treated these mice with EAO over ten days. Our findings revealed that EAO not only reduced the incidence of diabetes but also helped preserve pancreatic islets—critical for insulin production.
The results were promising as we observed significant immunomodulatory effects from the oregano extract. In vitro tests indicated that EAO suppressed the activation of immune cells, particularly macrophages and T lymphocytes. Furthermore, it appeared to decrease the levels of certain inflammatory T cell populations and their associated transcription factors, which play a role in promoting inflammation.
These discoveries suggest that oregano extract could potentially serve as a therapeutic option for managing type 1 diabetes by targeting the autoimmune responses involved in the disease. Overall, this study highlights an exciting avenue for plant-based treatments in diabetes management.
Read More
9
Oregano extract shows T1D promise
Methanolic extract of Origanum vulgare ameliorates type 1 diabetes through antioxidant, anti-inflammatory and anti-apoptotic activity.
Direct investigation of autoimmune treatment
We explored the potential benefits of Oregano, specifically its methanolic extract, for treating type 1 diabetes (T1D), an autoimmune condition characterized by the destruction of insulin-producing β-cells in the pancreas. In our study, we investigated this by using a group of mice that were subjected to a diabetes-inducing treatment with streptozotocin.
We found that the methanolic extract of Oregano, also known as MOE, showed promising results in reducing diabetes incidence compared to the aqueous extract. MOE not only helped to maintain normal insulin secretion but also acted as a powerful antioxidant, reducing harmful reactive oxygen and nitrogen species in the body. This is significant since oxidative stress can worsen the state of autoimmune diseases.
Additionally, our research revealed that MOE played a role in modulating the immune response. It reduced inflammation by affecting T helper cells, which are crucial in the immune response—but not in a way that would hurt the body’s defenses. Importantly, MOE seemed to protect the pancreatic β-cells from programmed cell death, a critical factor in the progression of diabetes.
While one prominent compound in MOE, rosmarinic acid, offered only partial protection, the overall findings suggest that multiple components in the extract contribute to its beneficial effects. Overall, it appears that Oregano's properties as an antioxidant, anti-inflammatory, and anti-apoptotic agent may help in managing T1D.
We found that the methanolic extract of Oregano, also known as MOE, showed promising results in reducing diabetes incidence compared to the aqueous extract. MOE not only helped to maintain normal insulin secretion but also acted as a powerful antioxidant, reducing harmful reactive oxygen and nitrogen species in the body. This is significant since oxidative stress can worsen the state of autoimmune diseases.
Additionally, our research revealed that MOE played a role in modulating the immune response. It reduced inflammation by affecting T helper cells, which are crucial in the immune response—but not in a way that would hurt the body’s defenses. Importantly, MOE seemed to protect the pancreatic β-cells from programmed cell death, a critical factor in the progression of diabetes.
While one prominent compound in MOE, rosmarinic acid, offered only partial protection, the overall findings suggest that multiple components in the extract contribute to its beneficial effects. Overall, it appears that Oregano's properties as an antioxidant, anti-inflammatory, and anti-apoptotic agent may help in managing T1D.
Read More
9.5
Oregano component improves immune regulation
A novel heat-shock protein coinducer boosts stress protein Hsp70 to activate T cell regulation of inflammation in autoimmune arthritis.
Focus on food and inflammation
We explored how a natural component found in oregano, known as carvacrol, can influence the body's immune response, particularly in the context of autoimmune arthritis. The study aimed to see if boosting the levels of heat-shock proteins like Hsp70 could help in regulating inflammation caused by the immune system.
Through both laboratory experiments and tests in mice, we found that carvacrol significantly increased the expression of Hsp70, which in turn enhanced T cell responses. This led to improved recognition of Hsp70 by T cells, suggesting that the immune system was effectively responding to this stress protein.
Furthermore, our results showed that carvacrol administration not only promoted the growth of protective T cells but also notably suppressed the symptoms of experimental arthritis. In fact, T cells taken from mice that had consumed carvacrol were capable of transferring this protective effect to other mice.
Overall, our findings indicate that dietary components like carvacrol can play a vital role in regulating immune responses, ultimately helping to manage inflammatory diseases like autoimmune arthritis.
Through both laboratory experiments and tests in mice, we found that carvacrol significantly increased the expression of Hsp70, which in turn enhanced T cell responses. This led to improved recognition of Hsp70 by T cells, suggesting that the immune system was effectively responding to this stress protein.
Furthermore, our results showed that carvacrol administration not only promoted the growth of protective T cells but also notably suppressed the symptoms of experimental arthritis. In fact, T cells taken from mice that had consumed carvacrol were capable of transferring this protective effect to other mice.
Overall, our findings indicate that dietary components like carvacrol can play a vital role in regulating immune responses, ultimately helping to manage inflammatory diseases like autoimmune arthritis.
Read More
Most Useful Reviews
9.5
SIBO relief
This is a potent "herbal antibiotic"! My SIBO (small intestinal bacterial overgrowth) symptoms have disappeared. I took three capsules three times a day for a month alongside medications to support my liver, as it's crucial for detoxification. After two weeks, I started a delayed-release probiotic to restore the right gut flora.
Read More
9.5
Infection recovery
This product is incredible! After contracting a skin-eating bacteria, I was amazed by the improvement I experienced within a day of taking oregano oil. I also manage autoimmune disorders like Crohn's disease and find this supplement very beneficial.
Read More
9.5
Inflammation relief
I used this oil as part of a program to address inflammation in my intestines, and it worked. It's a powerful antifungal and antibacterial agent that helped with infections and inflammation without side effects.
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Very Effective
Based on 3 Researches
9.2
9.5
Oregano component improves immune regulation
A novel heat-shock protein coinducer boosts stress protein Hsp70 to activate T cell regulation of inflammation in autoimmune arthritis.
Focus on food and inflammation
We explored how a natural component found in oregano, known as carvacrol, can influence the body's immune response, particularly in the context of autoimmune arthritis. The study aimed to see if boosting the levels of heat-shock proteins like Hsp70 could help in regulating inflammation caused by the immune system.
Through both laboratory experiments and tests in mice, we found that carvacrol significantly increased the expression of Hsp70, which in turn enhanced T cell responses. This led to improved recognition of Hsp70 by T cells, suggesting that the immune system was effectively responding to this stress protein.
Furthermore, our results showed that carvacrol administration not only promoted the growth of protective T cells but also notably suppressed the symptoms of experimental arthritis. In fact, T cells taken from mice that had consumed carvacrol were capable of transferring this protective effect to other mice.
Overall, our findings indicate that dietary components like carvacrol can play a vital role in regulating immune responses, ultimately helping to manage inflammatory diseases like autoimmune arthritis.
Through both laboratory experiments and tests in mice, we found that carvacrol significantly increased the expression of Hsp70, which in turn enhanced T cell responses. This led to improved recognition of Hsp70 by T cells, suggesting that the immune system was effectively responding to this stress protein.
Furthermore, our results showed that carvacrol administration not only promoted the growth of protective T cells but also notably suppressed the symptoms of experimental arthritis. In fact, T cells taken from mice that had consumed carvacrol were capable of transferring this protective effect to other mice.
Overall, our findings indicate that dietary components like carvacrol can play a vital role in regulating immune responses, ultimately helping to manage inflammatory diseases like autoimmune arthritis.
Read More
9
Oregano extract combats type 1 diabetes
Ethyl Acetate Extract of Origanum vulgare L. ssp. hirtum Prevents Streptozotocin-Induced Diabetes in C57BL/6 Mice.
Direct investigation of oregano's effects
We explored the potential of Origanum vulgare L. ssp. hirtum, commonly known as Greek oregano, in the realm of autoimmune disorders, particularly type 1 diabetes (T1D). This study specifically looked at how an ethyl acetate extract of oregano (EAO) could influence the development of T1D in mice.
To conduct the research, researchers induced type 1 diabetes in male C57BL/6 mice using multiple low doses of streptozotocin. They then treated these mice with EAO over ten days. Our findings revealed that EAO not only reduced the incidence of diabetes but also helped preserve pancreatic islets—critical for insulin production.
The results were promising as we observed significant immunomodulatory effects from the oregano extract. In vitro tests indicated that EAO suppressed the activation of immune cells, particularly macrophages and T lymphocytes. Furthermore, it appeared to decrease the levels of certain inflammatory T cell populations and their associated transcription factors, which play a role in promoting inflammation.
These discoveries suggest that oregano extract could potentially serve as a therapeutic option for managing type 1 diabetes by targeting the autoimmune responses involved in the disease. Overall, this study highlights an exciting avenue for plant-based treatments in diabetes management.
To conduct the research, researchers induced type 1 diabetes in male C57BL/6 mice using multiple low doses of streptozotocin. They then treated these mice with EAO over ten days. Our findings revealed that EAO not only reduced the incidence of diabetes but also helped preserve pancreatic islets—critical for insulin production.
The results were promising as we observed significant immunomodulatory effects from the oregano extract. In vitro tests indicated that EAO suppressed the activation of immune cells, particularly macrophages and T lymphocytes. Furthermore, it appeared to decrease the levels of certain inflammatory T cell populations and their associated transcription factors, which play a role in promoting inflammation.
These discoveries suggest that oregano extract could potentially serve as a therapeutic option for managing type 1 diabetes by targeting the autoimmune responses involved in the disease. Overall, this study highlights an exciting avenue for plant-based treatments in diabetes management.
Read More
9
Oregano extract shows T1D promise
Methanolic extract of Origanum vulgare ameliorates type 1 diabetes through antioxidant, anti-inflammatory and anti-apoptotic activity.
Direct investigation of autoimmune treatment
We explored the potential benefits of Oregano, specifically its methanolic extract, for treating type 1 diabetes (T1D), an autoimmune condition characterized by the destruction of insulin-producing β-cells in the pancreas. In our study, we investigated this by using a group of mice that were subjected to a diabetes-inducing treatment with streptozotocin.
We found that the methanolic extract of Oregano, also known as MOE, showed promising results in reducing diabetes incidence compared to the aqueous extract. MOE not only helped to maintain normal insulin secretion but also acted as a powerful antioxidant, reducing harmful reactive oxygen and nitrogen species in the body. This is significant since oxidative stress can worsen the state of autoimmune diseases.
Additionally, our research revealed that MOE played a role in modulating the immune response. It reduced inflammation by affecting T helper cells, which are crucial in the immune response—but not in a way that would hurt the body’s defenses. Importantly, MOE seemed to protect the pancreatic β-cells from programmed cell death, a critical factor in the progression of diabetes.
While one prominent compound in MOE, rosmarinic acid, offered only partial protection, the overall findings suggest that multiple components in the extract contribute to its beneficial effects. Overall, it appears that Oregano's properties as an antioxidant, anti-inflammatory, and anti-apoptotic agent may help in managing T1D.
We found that the methanolic extract of Oregano, also known as MOE, showed promising results in reducing diabetes incidence compared to the aqueous extract. MOE not only helped to maintain normal insulin secretion but also acted as a powerful antioxidant, reducing harmful reactive oxygen and nitrogen species in the body. This is significant since oxidative stress can worsen the state of autoimmune diseases.
Additionally, our research revealed that MOE played a role in modulating the immune response. It reduced inflammation by affecting T helper cells, which are crucial in the immune response—but not in a way that would hurt the body’s defenses. Importantly, MOE seemed to protect the pancreatic β-cells from programmed cell death, a critical factor in the progression of diabetes.
While one prominent compound in MOE, rosmarinic acid, offered only partial protection, the overall findings suggest that multiple components in the extract contribute to its beneficial effects. Overall, it appears that Oregano's properties as an antioxidant, anti-inflammatory, and anti-apoptotic agent may help in managing T1D.
Read More
User Reviews
USERS' SCORE
Good
Based on 9 Reviews
8.7
9.5
SIBO relief
This is a potent "herbal antibiotic"! My SIBO (small intestinal bacterial overgrowth) symptoms have disappeared. I took three capsules three times a day for a month alongside medications to support my liver, as it's crucial for detoxification. After two weeks, I started a delayed-release probiotic to restore the right gut flora.
Read More
9.5
Inflammation relief
I used this oil as part of a program to address inflammation in my intestines, and it worked. It's a powerful antifungal and antibacterial agent that helped with infections and inflammation without side effects.
9.5
Infection recovery
This product is incredible! After contracting a skin-eating bacteria, I was amazed by the improvement I experienced within a day of taking oregano oil. I also manage autoimmune disorders like Crohn's disease and find this supplement very beneficial.
8.8
Immune support
I take oregano oil regularly as it is a powerful antiseptic. The capsules are convenient, and I've experienced fewer colds and viruses, especially given my autoimmune disorder.
8.8
Post-antibiotic boost
This is a nice product of great quality. It helped improve my immunity after a course of antibiotics and effectively met my needs. I will order more.
